Center of Reproductology / Blog / An improved approach to comprehensive IVF programs

An improved approach to comprehensive IVF programs

ISIDA Clinic has introduced a new approach to comprehensive IVF programs. From now on, they include ICSI and vitrification – two powerful components of increasing the efficiency of in vitro fertilization.

The male aspect. Using the ICSI method

One of the main roles in successful fertilization is assigned to the sperm and its ability to reach the goal. The greater the number, the better the mobility and quality of male cells, the higher the probability of getting a result. However, even under optimal conditions, there are situations when fertilization does not occur. In 12% of cases, the causes of failures remain unknown. But using the ICSI method allows you to reduce the risk of failure by almost 6 times!

The term ICSI (Intra Cytoplasmic Sperm Injection) means “Injection of a sperm into the cytoplasm of an egg.” With the help of special micromanipulators, the embryologist makes a puncture in the egg and inserts a sperm into it. For fertilization, only one sperm is used, carefully selected on the basis of the correct structure and high mobility. In the course of use, this technique has proven its advantages: if the previously used in vitro method provided success in 65% of cases, then ICSI increased this indicator to 99%.

This technique made it possible to reduce the risks associated with sperm variability. Diseases, medication, any stressful situations on the eve of sperm collection can worsen its characteristics and reduce the chances of successful fertilization. And the ICSI technique allows you to take into account the peculiarities of each patient’s body and get the maximum result.

The female aspect. Preparation of the body and vitrification

For successful fertilization, it is important not only to obtain a high-quality embryo, but also to create optimal conditions for its development in the female body. The fact is that during the stimulation period, half of the women have unfavorable conditions for embryo implantation. Hormonal drugs used to stimulate the maturation of eggs can negatively affect the condition of the inner lining of the uterus, to which the embryo is attached. If the hormone level after stimulation is too high, it is recommended to wait until the next cycle for embryo transfer. This is possible due to embryo cryopreservation by vitrification, which is also used for ovarian hyperstimulation. With the help of vitrification, doctors can adjust to the cycle of the female body and transfer the embryo at the most favorable time for this.

Vitrification is a type of embryo freezing that guarantees a very high level of cell viability preservation. The procedure is carried out at the stage of 5-7 days of embryo maturation. When a favorable period for implantation comes, it is thawed and transferred to the body of the expectant mother. This significantly increases the effectiveness of pregnancy. Comprehensive IVF programs at ISIDA include embryo cryopreservation even when there is no need for embryo transfer to a later period. One of the resulting embryos is transferred, and the others are vitrified for possible pregnancy in the future.

“The ICSI method and vitrification gave us the opportunity to adapt to the individual characteristics of each patient’s body. By minimizing the risk at the stages of egg fertilization and embryo fixation in the body of the expectant mother, the effectiveness of IVF increases significantly – in women under 35, the probability of pregnancy on the first attempt reaches 60%! Thanks to the effectiveness of ICSI and vitrification, confidence in success is growing, which allows you to transfer only one embryo, excluding the onset of multiple pregnancies”, – says andrologist, geneticist, embryologist, endocrinologist of the ISIDA clinic Evgeniya Ulaeva.

For more information about comprehensive IVF programs, please contact the specialists of the ISIDA clinic!

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