Genetic Diagnosis
Preimplantation genetic diagnosis/screening (PGD/PGS) is a diagnostic procedure used in IVF treatment, in cases where there is a risk of developing the genetic disorders by the fetus.
ISIDA clinic was one of the the first in Ukraine to introduce an ultra-precise method of preimplantation genetic screening – the NGS method that allows one to detect any chromosome aberration or genetic disease caused by a known gene mutation. A distinctive feature of the NGS method is its high accuracy and certainty in detecting genetic anomalies.
NGS (Next Generation Sequencing) improves considerably the efficiency of IVF as even before embryo implantation, it allows detecting all the known chromosomal pathologies which approx. in 50% cases form the reason of the pregnancy failure during IVF program.
How do we perform NGS diagnostics
On the fifth day after fertilization of the embryo, it starts differentiating into intracellular mass which forms basis of the future fetus and into the external layer cells – trophectoderm that will participate in the embryo implantation into uterine cavity and will form fetal part of placenta.
For NGS analysis we take several trophectoderm cells, using highly precise tools. The possibility to damage the embryo in this moment is extremely low.
The cells taken for analysis will be checked with NGS method for genetic or\and chromosomal anomalies. The process is highly precise and allows to detect any genetic decease related to any known genetic decease. The result of the diagnostics with NGS method is 99,9% precise.
While waiting for the analysis results, the embryos are frozen by vitrification, the transfer of the diagnosed embryos shall be done in cryo-cycle preventing the risk of hyper-stimulation. This also improves the efficiency of the embryos implantation into uterine cavity.
PGD/PGS is highly recommended:
- if the mother is over the age of 35;
- in case of recurrent miscarriage;
- if there was a pregnancy with fetal chromosomal abnormalities in the past;
- in cases of several unsuccessful IVF attempts;
- in cases where one of the parents has chromosome translocations.
PGD\PGS analysis by NGS allows selecting a chromosomally normal embryo before implantation.
In addition, PGS allows determining the sex of the future baby.
Reviews
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Isida clinic has given us not one, but two babies! We did not expect it, but an ultrasound showed that we were blessed with two boys. Now we are worried doubly, but happy twice as much at the same time. We will be great parents of twins, no worries about that!
The best clinic and the most caring doctors! The best memories. It's a place you want to come back to:)
Myroslava Vatsyk is a very good specialist. She explains everything so clearly and helps you think positively and do positive things.
We are truly grateful for our two sons. Thanks to Myroslava Vatsyk I managed to get pregnant with the help of IVF. From the very beginning you gave us hope and belief. Thank you.
Having been to many doctors and clinics (to help me with my situation, I was suggested donor oocyte and operation), I turned to Doctor Svitlana Turbanist. She was the only one who suggested medical treatment, and I got pregnant naturally, which I wasn't even hoping for! Doctor Svetlana gave our family a big miracle!! We are extremely grateful to this doctor for her professionalism and experience.
Doctor Iryna Kapshuk, thank you for making my dream come true)) Lots of health to you.
Svitlana Shyiyanova, a huge thank you to you for our long awaited boy! Thank you for your professionalism, for the words of support and for helping us to finally become happy parents!
I would like to thank the whole staff for the treatment and for taking good care of us at your clinic. I am extremely grateful for your professionalism and human kindness. ISIDA clinic is indeed unique. Lots of health, inspiration and growth to everyone. Thank you for everything.
I am genuinely grateful to everyone in ISIDA clinic! Here I found peace and hope, kindness and comfort. I had to visit a lot for different reasons, and I have to admit that I love your clinic. Lots of happiness, prosperity and success to the clinic and to everyone there.
Thanks to this clinic, her wonderful team of professionals, we have a son born! I want to wish so much prosperity, joy and bright days to the whole staff of ISIDA clinic!