/ / Genetic Diagnosis

Genetic Diagnosis

Preimplantation genetic diagnosis/screening (PGD/PGS) is a diagnostic procedure used in IVF treatment, in cases where there is a risk of developing the genetic disorders by the fetus.

ISIDA clinic was one of the the first in Ukraine to introduce an ultra-precise method of preimplantation genetic screening – the NGS method that allows one to detect any chromosome aberration or  genetic disease caused by a known gene mutation. A distinctive feature of the NGS method is its high accuracy and certainty in detecting genetic anomalies.

NGS (Next Generation Sequencing) improves considerably the efficiency of IVF as even before embryo implantation, it allows detecting all the known chromosomal pathologies which approx. in 50% cases form the reason of the pregnancy failure during IVF program.

How do we perform NGS diagnostics

On the fifth day after fertilization of the embryo, it starts differentiating into intracellular mass which forms basis of the future fetus and into the external layer cells – trophectoderm that will participate in the embryo implantation into uterine cavity and will form fetal part of placenta.

For NGS analysis we take several trophectoderm cells, using highly precise tools. The possibility to damage the embryo in this moment is extremely low.

The cells taken for analysis will be checked with NGS method for genetic or\and chromosomal anomalies. The process is highly precise and allows to detect any genetic decease related to any known genetic decease. The result of the diagnostics with NGS method is 99,9% precise.

While waiting for the analysis results, the embryos are frozen by vitrification, the transfer of the diagnosed embryos shall be done in cryo-cycle preventing the risk of hyper-stimulation. This also improves the efficiency of the embryos implantation into uterine cavity.

PGD/PGS is highly recommended:

  • if the mother is over the age of 35;
  • in case of recurrent miscarriage;
  • if there was a pregnancy with fetal chromosomal abnormalities in the past;
  • in cases of several unsuccessful IVF attempts;
  • in cases where one of the parents has chromosome translocations.

PGD\PGS analysis by NGS allows selecting a chromosomally normal embryo before implantation.

In addition, PGS allows determining the sex of the future baby.

 

 

Reviews

Rebecca from France March 15, 2022
Rebecca from France March 15, 2022

I want to thank ISIDA clinic, for making my dream come true. Right away, I felt like I came to the right place. My doctor was Inna Moroz. She has a lot of experience, she is very professional but also knows how to reassure when you are having a hard time, which was my case when I was transferring my baby girl. My coordinator was Alina, who is a lovely person. She is very reactive, helpful, and also very professional. She helped me many times and always answered my questions, not only concerning the medical procedure but also organizing my trip to Kyiv. Everyone at ISIDA is very professional and trustworthy. I couldn't make a better choice. A part of my heart will always stay in Ukraine.

I want to thank ISIDA clinic, for making my dream come true. Right away, I felt like I came to the right place. My doctor was Inna Moroz. She has a lot of experience, she is very professional but also knows how to reassure when you are having a hard time, which was my case when I was transferring my baby girl. My coordinator was Alina, who is a lovely person. She is very reactive, helpful, and also very professional. She helped me many times and always answered my questions, not only concerning the medical procedure but also organizing my trip to Kyiv. Everyone at ISIDA is very professional and trustworthy. I couldn't make a better choice. A part of my heart will always stay in Ukraine.

Klaudia from Britain Dec. 30, 2021
Klaudia from Britain Dec. 30, 2021

We chose Isida after two failed ivf cycles in Cyprus. Our co-ordinator Natasha was amazing and she has really held our hand through the whole process. Not only do co-ordinators help with the medical process but they also help with recommendations for hotels, transport, pharmacies and even covid testing too! I was also astonished that most co-ordinators speak 2-3 languages!

The clinic has done very thorough pre-testing which meant that our ivf protocol was personalised to our circumstances. Our doctor, Dr Inna Moroz, was professional and friendly and has always taken time to answer our questions. I’m pleased to say that we were successful with Isida on our very first try and we now have a healthy baby girl! I have recommended this clinic to many people since and I wish I had found it sooner.

Maria from Sweden Nov. 17, 2021
Maria from Sweden Nov. 17, 2021

Thank you words to Isida

Dear Isida, From the bottom of our hearts we want to thank you for your professionalism and for making our dream come true. Our perfect daughter is a true blessing after a long and hard struggle. Before we found Isida we tried clinics in both Crete and Cyprus with bad results. However our first attempt at Isida was a success. Our coordinator Nataliia went above and beyond to help us in every way possible. Without any doubt the best coordinator I’ve met. Dr Inna always had a soft approach and was really kind. We will be forever greatful and we can’t thank you enough.

Anne May 27, 2020
Anne May 27, 2020

I would like to thank the entire staff of the Isida clinic who helped me give birth to a wonderful little girl. The remote monitoring was perfect and the reception on site was excellent. I immediately felt reassured in this clinic, which was not the case in France, Spain or Russia. Dr. Inna Moroz was able to explain the treatment to me clearly and took into account both my health and that of the baby. The team was always able to reassure me in the face of my anxieties. I’ll come back next year for my second child. I would recommend without hesitation the Isida clinic which allowed me to realize my dream of becoming a mother from the first attempt! Many thanks and bravo for your expertise and your kindness!

I would like to thank the entire staff of the Isida clinic who helped me give birth to a wonderful little girl. The remote monitoring was perfect and the reception on site was excellent. I immediately felt reassured in this clinic, which was not the case in France, Spain or Russia. Dr. Inna Moroz was able to explain the treatment to me clearly and took into account both my health and that of the baby. The team was always able to reassure me in the face of my anxieties. I’ll come back next year for my second child. I would recommend without hesitation the Isida clinic which allowed me to realize my dream of becoming a mother from the first attempt! Many thanks and bravo for your expertise and your kindness!

Ioannina May 13, 2019
Ioannina May 13, 2019

Dear Turbanist Svetlana! I want to thank you for your work and just for being there! Only thanks to you, my husband and I became the parents of a beautiful baby! You gave me hope when doctors in my country refused to work with me. You said that everything will work out and everything did work out!

Dear Turbanist Svetlana! I want to thank you for your work and just for being there! Only thanks to you, my husband and I became the parents of a beautiful baby! You gave me hope when doctors in my country refused to work with me. You said that everything will work out and everything did work out!

Iren May 10, 2019
Iren May 10, 2019

Sadovoy Andrei, thank you so much. Our son is already 7.5 months. Every day my husband and I thank you. You are a magician! We wish you Health!

Sadovoy Andrei, thank you so much. Our son is already 7.5 months. Every day my husband and I thank you. You are a magician! We wish you Health!

Oxana April 29, 2019
Oxana April 29, 2019

Dr. Svetlana Turbanist! Vielen Dank für die lang ersehnten Kinder !!! Möge Gott Ihnen Gesundheit und Segen geben !!!

Dr. Svetlana Turbanist! Vielen Dank für die lang ersehnten Kinder !!! Möge Gott Ihnen Gesundheit und Segen geben !!!

Xenia April 22, 2019
Xenia April 22, 2019

We are very grateful to Sadovy Andrei for our little son. We wish you health!

We are very grateful to Sadovy Andrei for our little son. We wish you health!

Helen April 17, 2019
Helen April 17, 2019

I want to thank Kseniia Khazhylenko on behalf of our entire family !!!!!! Ksenia Georgievna, thank you very much !!!!!!! After seven years of endless visits to doctors and tests, a little more than half a year after we met you in ISIDA Clinic, our family finally heard the long-awaited words of congratulations on fact that we got a confirmed pregnancy!

I want to thank Kseniia Khazhylenko on behalf of our entire family !!!!!! Ksenia Georgievna, thank you very much !!!!!!! After seven years of endless visits to doctors and tests, a little more than half a year after we met you in ISIDA Clinic, our family finally heard the long-awaited words of congratulations on fact that we got a confirmed pregnancy! Ksenia, I wish you health, happiness and patience in your work! It’s hard to imagine how emotionally difficult it is to endure all the patient’s stories, to find the right approach and the right words for everyone! I wish for you to grow professionally and i wish for you to get more opportunities to develop your skills. I would like to wish the clinic prosperity! Let there never be problems with qualified personnel and investors !!!!!

Magdalena March 27, 2019
Magdalena March 27, 2019

Dziękuję Svetlana Shiyanova! Ciąża nadeszła! Magdalena, Warszawa

Dziękuję Svetlana Shiyanova! Ciąża nadeszła! Magdalena, Warszawa

Lyudmila & Ihor March 4, 2019
Lyudmila & Ihor March 4, 2019

My husband and I, for 15 years we had been looking for a person who would help us become parents. Thank God we finally found her. Dear Svetlana, you are extremely intelligent and talented. We very much appreciate your help! You made a miracle for us. Thanks to you we heard these long-awaited words "Mum and Dad"! Thank you so much!

My husband and I, for 15 years we had been looking for a person who would help us become parents. Thank God we finally found her. Dear Svetlana, you are extremely intelligent and talented. We very much appreciate your help! You made a miracle for us. Thanks to you we heard these long-awaited words "Mum and Dad"! Thank you so much!

Kseniia Feb. 10, 2019
Kseniia Feb. 10, 2019

Svetlana Turbanist – is a real professional, attentive and sensitive person! My husband and I are eternally happy that we met this particular doctor! With her help, we welcomed our long-awaited daughter) We are grateful to ISIDA for our happiness! Wish you prosperity and success!

Svetlana Turbanist – is a real professional, attentive and sensitive person! My husband and I are eternally happy that we met this particular doctor! With her help, we welcomed our long-awaited daughter) We are grateful to ISIDA for our happiness! Wish you prosperity and success!