Genetic Diagnosis
Preimplantation genetic diagnosis/screening (PGD/PGS) is a diagnostic procedure used in IVF treatment, in cases where there is a risk of developing the genetic disorders by the fetus.
ISIDA clinic was one of the the first in Ukraine to introduce an ultra-precise method of preimplantation genetic screening – the NGS method that allows one to detect any chromosome aberration or genetic disease caused by a known gene mutation. A distinctive feature of the NGS method is its high accuracy and certainty in detecting genetic anomalies.
NGS (Next Generation Sequencing) improves considerably the efficiency of IVF as even before embryo implantation, it allows detecting all the known chromosomal pathologies which approx. in 50% cases form the reason of the pregnancy failure during IVF program.
How do we perform NGS diagnostics
On the fifth day after fertilization of the embryo, it starts differentiating into intracellular mass which forms basis of the future fetus and into the external layer cells – trophectoderm that will participate in the embryo implantation into uterine cavity and will form fetal part of placenta.
For NGS analysis we take several trophectoderm cells, using highly precise tools. The possibility to damage the embryo in this moment is extremely low.
The cells taken for analysis will be checked with NGS method for genetic or\and chromosomal anomalies. The process is highly precise and allows to detect any genetic decease related to any known genetic decease. The result of the diagnostics with NGS method is 99,9% precise.
While waiting for the analysis results, the embryos are frozen by vitrification, the transfer of the diagnosed embryos shall be done in cryo-cycle preventing the risk of hyper-stimulation. This also improves the efficiency of the embryos implantation into uterine cavity.
PGD/PGS is highly recommended:
- if the mother is over the age of 35;
- in case of recurrent miscarriage;
- if there was a pregnancy with fetal chromosomal abnormalities in the past;
- in cases of several unsuccessful IVF attempts;
- in cases where one of the parents has chromosome translocations.
PGD\PGS analysis by NGS allows selecting a chromosomally normal embryo before implantation.
In addition, PGS allows determining the sex of the future baby.
Reviews

I want to thank ISIDA clinic, for making my dream come true. Right away, I felt like I came to the right place. My doctor was Inna Moroz. She has a lot of experience, she is very professional but also knows how to reassure when you are having a hard time, which was my case when I was transferring my baby girl. My coordinator was Alina, who is a lovely person. She is very reactive, helpful, and also very professional. She helped me many times and always answered my questions, not only concerning the medical procedure but also organizing my trip to Kyiv. Everyone at ISIDA is very professional and trustworthy. I couldn't make a better choice. A part of my heart will always stay in Ukraine.

We chose Isida after two failed ivf cycles in Cyprus. Our co-ordinator Natasha was amazing and she has really held our hand through the whole process. Not only do co-ordinators help with the medical process but they also help with recommendations for hotels, transport, pharmacies and even covid testing too! I was also astonished that most co-ordinators speak 2-3 languages!

I would like to thank the entire staff of the Isida clinic who helped me give birth to a wonderful little girl. The remote monitoring was perfect and the reception on site was excellent. I immediately felt reassured in this clinic, which was not the case in France, Spain or Russia. Dr. Inna Moroz was able to explain the treatment to me clearly and took into account both my health and that of the baby. The team was always able to reassure me in the face of my anxieties. I’ll come back next year for my second child. I would recommend without hesitation the Isida clinic which allowed me to realize my dream of becoming a mother from the first attempt! Many thanks and bravo for your expertise and your kindness!

Dear Turbanist Svetlana! I want to thank you for your work and just for being there! Only thanks to you, my husband and I became the parents of a beautiful baby! You gave me hope when doctors in my country refused to work with me. You said that everything will work out and everything did work out!

Sadovoy Andrei, thank you so much. Our son is already 7.5 months. Every day my husband and I thank you. You are a magician! We wish you Health!

Dr. Svetlana Turbanist! Vielen Dank für die lang ersehnten Kinder !!! Möge Gott Ihnen Gesundheit und Segen geben !!!

We are very grateful to Sadovy Andrei for our little son. We wish you health!

I want to thank Kseniia Khazhylenko on behalf of our entire family !!!!!! Ksenia Georgievna, thank you very much !!!!!!! After seven years of endless visits to doctors and tests, a little more than half a year after we met you in ISIDA Clinic, our family finally heard the long-awaited words of congratulations on fact that we got a confirmed pregnancy!

Dziękuję Svetlana Shiyanova! Ciąża nadeszła! Magdalena, Warszawa

My husband and I, for 15 years we had been looking for a person who would help us become parents. Thank God we finally found her. Dear Svetlana, you are extremely intelligent and talented. We very much appreciate your help! You made a miracle for us. Thanks to you we heard these long-awaited words "Mum and Dad"! Thank you so much!

Svetlana Turbanist – is a real professional, attentive and sensitive person! My husband and I are eternally happy that we met this particular doctor! With her help, we welcomed our long-awaited daughter) We are grateful to ISIDA for our happiness! Wish you prosperity and success!