Genetic Diagnosis
Preimplantation genetic diagnosis/screening (PGD/PGS) is a diagnostic procedure used in IVF treatment, in cases where there is a risk of developing the genetic disorders by the fetus.
ISIDA clinic was one of the the first in Ukraine to introduce an ultra-precise method of preimplantation genetic screening – the NGS method that allows one to detect any chromosome aberration or genetic disease caused by a known gene mutation. A distinctive feature of the NGS method is its high accuracy and certainty in detecting genetic anomalies.
NGS (Next Generation Sequencing) improves considerably the efficiency of IVF as even before embryo implantation, it allows detecting all the known chromosomal pathologies which approx. in 50% cases form the reason of the pregnancy failure during IVF program.
How do we perform NGS diagnostics
On the fifth day after fertilization of the embryo, it starts differentiating into intracellular mass which forms basis of the future fetus and into the external layer cells – trophectoderm that will participate in the embryo implantation into uterine cavity and will form fetal part of placenta.
For NGS analysis we take several trophectoderm cells, using highly precise tools. The possibility to damage the embryo in this moment is extremely low.
The cells taken for analysis will be checked with NGS method for genetic or\and chromosomal anomalies. The process is highly precise and allows to detect any genetic decease related to any known genetic decease. The result of the diagnostics with NGS method is 99,9% precise.
While waiting for the analysis results, the embryos are frozen by vitrification, the transfer of the diagnosed embryos shall be done in cryo-cycle preventing the risk of hyper-stimulation. This also improves the efficiency of the embryos implantation into uterine cavity.
PGD/PGS is highly recommended:
- if the mother is over the age of 35;
- in case of recurrent miscarriage;
- if there was a pregnancy with fetal chromosomal abnormalities in the past;
- in cases of several unsuccessful IVF attempts;
- in cases where one of the parents has chromosome translocations.
PGD\PGS analysis by NGS allows selecting a chromosomally normal embryo before implantation.
In addition, PGS allows determining the sex of the future baby.
Reviews
Svitlana Shyiyanova, a huge thank you to you for our long awaited boy! Thank you for your professionalism, for the words of support and for helping us to finally become happy parents!
I would like to thank the whole staff for the treatment and for taking good care of us at your clinic. I am extremely grateful for your professionalism and human kindness. ISIDA clinic is indeed unique. Lots of health, inspiration and growth to everyone. Thank you for everything.
I am genuinely grateful to everyone in ISIDA clinic! Here I found peace and hope, kindness and comfort. I had to visit a lot for different reasons, and I have to admit that I love your clinic. Lots of happiness, prosperity and success to the clinic and to everyone there.
Thanks to this clinic, her wonderful team of professionals, we have a son born! I want to wish so much prosperity, joy and bright days to the whole staff of ISIDA clinic!
Great structure, high professionality and competences. Thanks at all the staff and especially to Yuliia, our personal assistant. Finally you realized our dream of a big family!!!
Vatsik Miroslava is very good and intelligent doctor! We are so grateful to her for helping us and our little long-awaited happiness, that we have now!
Svetlana Shiyanova is a very good doctor, she will always support you! We had a long way to our happiness, but I got pregnant and we have a sweet son thanks to her. Thank you very much for our miracle! May God give you all the best!
Dear ISIDA! I want to thank your professional team and say thank you for the calmness, empathy and really professional doctors` attitude to their patients. Two years ago I came to Sadovoy Andrey Petrovich, and today I gave birth to two beautiful children. Thanks to the doctor, real professional who treated and performed operations, monitored all processes with a soul. The best doctor in Kiev!
After going through many attempts that didn`t lead to the birth of a child in other clinics, we turned to Svetlana Vladimirovna Shiyanova in ISIDA. We believed that we will succeed this time, from the first meeting with her. And, yes, yes - "It's a girl"!!! Thank you very much for your professionalism and simply human attention!
Andrei Petrovich Sadovoy and I have passed a long way, several difficult failures ... I want to note that it is very important to choose your doctor. He is very professional doctor and sincere person! Sometimes he was too straightforward, (maybe somebody takes it for being rude), but I have never even thought of changing a doctor. Thanks to him, I finally became a mother at 43, despite all the failed predictions! With great warmth we remember him and his assistant Julia Dovgal. We wish you patience and all the best sincerely! With love and great respect to you!
Добрый день всем! Сегодня нашему сыночку исполнилось три месяца, и это замечательный повод поблагодарить клинику и всех, кто помог появится на свет нашему маленькому счастью! Хочу от нашей семьи выразить огромную благодарность: Руководству Исиды за организацию социальной программы по бесплатному лечению бесплодия для 5ти пар в 2016году...
Dear ISIDA, This is our little way of appreciate you all for what God has done in my family through ISIDA. The IVF team were superb, wonderful and amazing. Special thanks to Anna Shtokalova and Yulia for your support in making everything a success. Our Baby is 7 months old and growing fast/healthy.... Thanks and God bless ISIDA.