Kryozyklus

 Die Vitrifikation ist eine Art des FrostensderEmbryonen,dieinder Stillsetzung aller biologischen Prozesse in den Zellen durch die Einfrostung und ihre weitere Erhaltung bei tiefen Temperaturen besteht,und einensehr hohen Stand der Erhaltung der Lebensfähigkeitvon Zellen garantiert. DieWesenheitderVitrifikationbesteht in der Anwendung der hohen Konzentrationen des Kryoprotektors, wodurch es gelingt, die Bildung der Eiskristalle – der Hauptursache der intrazellulären Beschädigungen, von denen die vorherige Methode des FrostensderEmbryonen begleitet wurde, zu vermeiden. DieProzedurwirdim Stadium von 5-7 Tagen der Reifung des Embryosdurchgeführt. WenneingünstigerZeitraum für seine Implantation eintritt, wird er entfrostet und in den Organismus der werdenden Mutter transferieren.

DieVerwendungdergefrostetenEmbryonenbei wiederholten Zyklen der Behandlung heißt der Kryozyklus. InsolchemZyklusderBehandlungwirddieStimulation derSupereisprunginduktion nicht durchgeführt, und die eingetretene Schwangerschaft verläuft bei minderer hormonaler Körperbelastung der werdenden Mutter. Das steigert maßgeblich die Effektivität des Eintritts der Schwangerschaft.

Die Durchführung des Kryozyklusist in folgenden Fällen empfohlen:

  • nachdem erfolglosen Versuch der extrakorporalen Befruchtung;
  • wenndasEhepaar bei der Planung dererstenextrakorporalen Befruchtung die Pläne für das zweite und das dritte Kind bereits hat;
  • beimVorhandenseineineronkologischen Erkrankung, deren Behandlung weitere Zeugungsfähigkeit beeinflussen kann;
  • Vorhandenseinder Zuckerkrankheit oder Azoospermie bei den Männern.

DieAnwendungdesKryozyklushat eine Reihe von Vorteilen für den Patienten, darunter:

  • erheblicheRisikoverminderung der Entwicklung der schwierigen Komplikationder extrakorporalen Befruchtung– des ovariellen Hyperstimulationssyndroms. ImErgebnisderOvulationsförderung ergibt sich gewöhnlicheine Menge von den Eizellen, die befruchtet werden, und die erhaltenen Embryonenwerden gefrostet. Dasermöglicht, schonin1-2 ZyklendenKryozyklusmit der Effektivität, die dem Transfer im «frischen» Zyklus gleich ist, durchzuführen;
  • finanzielleKostensenkungder Patienten in den Fällen, wenn sich der erste Versuch der extrakorporalen Befruchtungals erfolglos erwiesen hat - der Kryozyklusermöglicht, die wiederholte Ovulationsförderungund die Benutzung dafür der teuren Arzneimittelzu vermeiden.
  • derKryozyklusermöglichtdenPatientinnen mit einem niedrigen Follikelpool die Embryonenanzusparen, sowie die Eizellen in den Fällen, dass die Frau kraft persönlicher Gründe die Schwangerschaft in den nächsten Jahren nicht plant, zu erhalten.

In der Welt sind riesengroße Arbeitserfahrungen mit dem vitrifizierten Material gesammelt. Esisterwiesen, dasseskeineHäufigkeitsunterschiede der angeborenen Missbildungen bei den Kindern, die im Ergebnis der spontanen Schwangerschaften geboren wurden, und bei den Kindern, die aus den entfrostetenEmbryonenerschienen sind, gibt. NachdemEntfrostenistdie ÜberlebensfähigkeitdesBiomaterialssehr hoch (mindestens 95%). Aber es ist wichtig, zu verstehen, dass sich ein kleines Prozent von Eizellen nach dem Entfrostenals untauglich zur Befruchtung erweisen könnenoder die Probleme mit der Blastulation haben können. Es ist leider unmöglich, das vor der Durchführung der Prozedur festzustellen.

DieextrakorporaleBefruchtungimKryozyklushatbei ISIDA einen überaus hohen Stand erreicht –seit zwei Jahren ist die Effektivität um das Doppelte, bis 60% erfolgreiche Implantationen, durch die Anwendung der modernen Methode der Vitrifikation des Embryos gestiegen. Das ist ein sehr hoher Stand, der von führenden europäischen Kliniken demonstriert wird. UndsolcheHochleistungenwerdenbeim Transfer in der überwiegenden Mehrheit von Fällen von 1 Blastozyste/Embryoerreicht. Daswurdemöglichdank der hervorragenden Arbeitdes embryologischen Dienstes – der Fachleute, Ausrüstung und Arbeitsverfahren.

DieKomplexprogrammederextrakorporalenBefruchtungschließen bei ISIDA die KryokonservierungderEmbryonen sogar in jenem Fall, wenn es keinen Bedarf am Embryotransferfür einen späteren Zeitraum gibt, ein. Eindererhaltenen Embryonen wird transferiert, und andere Embryonenwerden für eventuelle Schwangerschaft in der Zukunft vitrifiziert.

 

Referenzen

Rebecca from France 15. März 2022
Rebecca from France 15. März 2022

I want to thank ISIDA clinic, for making my dream come true. Right away, I felt like I came to the right place. My doctor was Inna Moroz. She has a lot of experience, she is very professional but also knows how to reassure when you are having a hard time, which was my case when I was transferring my baby girl. My coordinator was Alina, who is a lovely person. She is very reactive, helpful, and also very professional. She helped me many times and always answered my questions, not only concerning the medical procedure but also organizing my trip to Kyiv. Everyone at ISIDA is very professional and trustworthy. I couldn't make a better choice. A part of my heart will always stay in Ukraine.

I want to thank ISIDA clinic, for making my dream come true. Right away, I felt like I came to the right place. My doctor was Inna Moroz. She has a lot of experience, she is very professional but also knows how to reassure when you are having a hard time, which was my case when I was transferring my baby girl. My coordinator was Alina, who is a lovely person. She is very reactive, helpful, and also very professional. She helped me many times and always answered my questions, not only concerning the medical procedure but also organizing my trip to Kyiv. Everyone at ISIDA is very professional and trustworthy. I couldn't make a better choice. A part of my heart will always stay in Ukraine.

Klaudia from Britain 30. Dezember 2021
Klaudia from Britain 30. Dezember 2021

We chose Isida after two failed ivf cycles in Cyprus. Our co-ordinator Natasha was amazing and she has really held our hand through the whole process. Not only do co-ordinators help with the medical process but they also help with recommendations for hotels, transport, pharmacies and even covid testing too! I was also astonished that most co-ordinators speak 2-3 languages!

The clinic has done very thorough pre-testing which meant that our ivf protocol was personalised to our circumstances. Our doctor, Dr Inna Moroz, was professional and friendly and has always taken time to answer our questions. I’m pleased to say that we were successful with Isida on our very first try and we now have a healthy baby girl! I have recommended this clinic to many people since and I wish I had found it sooner.

Maria from Sweden 17. November 2021
Maria from Sweden 17. November 2021

Thank you words to Isida

Dear Isida, From the bottom of our hearts we want to thank you for your professionalism and for making our dream come true. Our perfect daughter is a true blessing after a long and hard struggle. Before we found Isida we tried clinics in both Crete and Cyprus with bad results. However our first attempt at Isida was a success. Our coordinator Nataliia went above and beyond to help us in every way possible. Without any doubt the best coordinator I’ve met. Dr Inna always had a soft approach and was really kind. We will be forever greatful and we can’t thank you enough.

Anne 27. Mai 2020
Anne 27. Mai 2020

I would like to thank the entire staff of the Isida clinic who helped me give birth to a wonderful little girl. The remote monitoring was perfect and the reception on site was excellent. I immediately felt reassured in this clinic, which was not the case in France, Spain or Russia. Dr. Inna Moroz was able to explain the treatment to me clearly and took into account both my health and that of the baby. The team was always able to reassure me in the face of my anxieties. I’ll come back next year for my second child. I would recommend without hesitation the Isida clinic which allowed me to realize my dream of becoming a mother from the first attempt! Many thanks and bravo for your expertise and your kindness!

I would like to thank the entire staff of the Isida clinic who helped me give birth to a wonderful little girl. The remote monitoring was perfect and the reception on site was excellent. I immediately felt reassured in this clinic, which was not the case in France, Spain or Russia. Dr. Inna Moroz was able to explain the treatment to me clearly and took into account both my health and that of the baby. The team was always able to reassure me in the face of my anxieties. I’ll come back next year for my second child. I would recommend without hesitation the Isida clinic which allowed me to realize my dream of becoming a mother from the first attempt! Many thanks and bravo for your expertise and your kindness!

Ioannina 13. Mai 2019
Ioannina 13. Mai 2019

Dear Turbanist Svetlana! I want to thank you for your work and just for being there! Only thanks to you, my husband and I became the parents of a beautiful baby! You gave me hope when doctors in my country refused to work with me. You said that everything will work out and everything did work out!

Dear Turbanist Svetlana! I want to thank you for your work and just for being there! Only thanks to you, my husband and I became the parents of a beautiful baby! You gave me hope when doctors in my country refused to work with me. You said that everything will work out and everything did work out!

Iren 10. Mai 2019
Iren 10. Mai 2019

Sadovoy Andrei, thank you so much. Our son is already 7.5 months. Every day my husband and I thank you. You are a magician! We wish you Health!

Sadovoy Andrei, thank you so much. Our son is already 7.5 months. Every day my husband and I thank you. You are a magician! We wish you Health!

Oxana 29. April 2019
Oxana 29. April 2019

Dr. Svetlana Turbanist! Vielen Dank für die lang ersehnten Kinder !!! Möge Gott Ihnen Gesundheit und Segen geben !!!

Dr. Svetlana Turbanist! Vielen Dank für die lang ersehnten Kinder !!! Möge Gott Ihnen Gesundheit und Segen geben !!!

Xenia 22. April 2019
Xenia 22. April 2019

We are very grateful to Sadovy Andrei for our little son. We wish you health!

We are very grateful to Sadovy Andrei for our little son. We wish you health!

Helen 17. April 2019
Helen 17. April 2019

I want to thank Kseniia Khazhylenko on behalf of our entire family !!!!!! Ksenia Georgievna, thank you very much !!!!!!! After seven years of endless visits to doctors and tests, a little more than half a year after we met you in ISIDA Clinic, our family finally heard the long-awaited words of congratulations on fact that we got a confirmed pregnancy!

I want to thank Kseniia Khazhylenko on behalf of our entire family !!!!!! Ksenia Georgievna, thank you very much !!!!!!! After seven years of endless visits to doctors and tests, a little more than half a year after we met you in ISIDA Clinic, our family finally heard the long-awaited words of congratulations on fact that we got a confirmed pregnancy! Ksenia, I wish you health, happiness and patience in your work! It’s hard to imagine how emotionally difficult it is to endure all the patient’s stories, to find the right approach and the right words for everyone! I wish for you to grow professionally and i wish for you to get more opportunities to develop your skills. I would like to wish the clinic prosperity! Let there never be problems with qualified personnel and investors !!!!!

Magdalena 27. März 2019
Magdalena 27. März 2019

Dziękuję Svetlana Shiyanova! Ciąża nadeszła! Magdalena, Warszawa

Dziękuję Svetlana Shiyanova! Ciąża nadeszła! Magdalena, Warszawa

Lyudmila & Ihor 4. März 2019
Lyudmila & Ihor 4. März 2019

My husband and I, for 15 years we had been looking for a person who would help us become parents. Thank God we finally found her. Dear Svetlana, you are extremely intelligent and talented. We very much appreciate your help! You made a miracle for us. Thanks to you we heard these long-awaited words "Mum and Dad"! Thank you so much!

My husband and I, for 15 years we had been looking for a person who would help us become parents. Thank God we finally found her. Dear Svetlana, you are extremely intelligent and talented. We very much appreciate your help! You made a miracle for us. Thanks to you we heard these long-awaited words "Mum and Dad"! Thank you so much!

Kseniia 10. Februar 2019
Kseniia 10. Februar 2019

Svetlana Turbanist – is a real professional, attentive and sensitive person! My husband and I are eternally happy that we met this particular doctor! With her help, we welcomed our long-awaited daughter) We are grateful to ISIDA for our happiness! Wish you prosperity and success!

Svetlana Turbanist – is a real professional, attentive and sensitive person! My husband and I are eternally happy that we met this particular doctor! With her help, we welcomed our long-awaited daughter) We are grateful to ISIDA for our happiness! Wish you prosperity and success!