Prenatal screening of fetal developmental disorders in the ISIDA clinic: modern equipment and new screening algorithms
The most important question that every woman will wonder almost from the first minutes of pregnancy until the very birth – “Is my baby healthy?”. And in order to answer this question as accurately as possible, as well as to prevent possible health problems for the unborn child, we use the best screening programs for prenatal diagnosis of fetal development disorders in the ISIDA clinic.
The ISIDA clinic has two own laboratories: clinical diagnostic and genetic. In these laboratories work highly qualified staff, professors, candidates of science, specialists with the highest category in the field of laboratory diagnostics. But the high accuracy of the results of their work primarily depends on high-quality laboratory equipment of expert class. That is why in our clinic for prenatal screening we use the PerkinElmer DELFIA Xpress automatic risk assessment analyzer in LifeCycle. This is the only program that allows to calculate the cumulative risk of the first and second trimesters in the phased implementation of screening.
Screening programs for prenatal diagnosis of fetal developmental disorders include ultrasound, biochemical, and genetic markers. The ISIDA clinic uses certified FetalMedicineFoundation (FMF) software to calculate the risk of chromosomal pathology of the fetus that based on ultrasound and biochemical screening results.
We are proud that a new prenatal screening algorithm for the first trimester was developed in the ISIDA clinic. It includes four biochemical markers - PAPP-A, freehCGß, PlGF and AFP quadro-test, which provides a more accurate determination of the high risk of developing pathologies in the fetus about 98% compared to competitive programs.
In addition, the combined screening protocol at the ISIDA clinic allows an assessment of the risk of preeclampsia with a sensitivity of 96%. After all, preeclampsia is one of the most frequent and severe complications of pregnancy - occurs in 5-10% cases of the general population. Early detection of high risk of preeclampsia significantly affects the outcome of pregnancy, the appointment of prophylactic treatment can reduce the risk of premature birth and intrauterine growth retardation by more than two times.
Thanks to the newest PerkinElmer DELFIA Xpress equipment with DelfiaXpress test kits and LifeCycle risk assessment, specialists in the ISIDA clinic can accurately calculate the risks of chromosomal abnormalities and preeclampsia, test for Down syndrome in the first trimester and screen for the earliest gestation.