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Genetic testing by PCR to determine the implantation window

Genetic testing by PCR to determine the implantation window

All patients who decide to participate in an IVF program are worried about how likely they are to get pregnant on the first try, what factors affect their effectiveness, and whether it is possible to increase the chances of pregnancy.

The doctors at ISIDA Clinic are always ready to give the most detailed answers to all the questions of their patients, tell them about the achievements of modern reproductology, and help them make an informed decision about choosing one or another variant of the IVF program. Among the factors by which it is possible to increase the effectiveness of IVF is the method for determining endometrial receptivity (REpoint).

“Usually, the endometrial condition for embryo implantation is assessed by ultrasonic and hormonal methods, but today there are already incomparably more accurate molecular instruments that make it possible to determine the optimal time for“ implanting ” a fertilized egg,” -  says Svetlana Shiyanova, head of the reproductology service, reproductologist.

Using the PCR method (polymerase chain reaction), it is possible to determine in real time the genes responsible for the process of changing the endometrium and establish the so-called implantation window.

The implantation window is a personalized time of the greatest receptivity of the endometrium. During this time, the embryo attaches to the mucous membrane of the uterine cavity.

According to modern research, about a quarter of patients undergoing ART programs have repeated implantation losses, which means that personalization of the time of embryo transfer (PET) is an urgent manipulation.

“The use of genetic testing by PCR to determine the implantation window even with the 1st IVF attempt gives an increase in PR by 25% and an improvement in the bearing of the first trimester by 11%,” - emphasizes Svetlana Shiyanova.

The procedure is prescribed by a reproductologist, who is guided by a list of indications for analysis.

The main indications for the assignment of testing are as follows:

* Repeated failed implants in IVF programs.

* Planning for embryo transfer (ET) after preimplantation genetic diagnosis (ASG).

* Suspicion of a change (lengthening) in the implantation window in patients with habitual pregnancy loss.

To find out the price of the procedure for determining endometrial receptivity (REpoint)- write our managers. For the procedure, three visits to the clinic are required.